A negative correlation between intron size and recombination rate has been reported for the Drosophila melanogaster and human genomes. Population-genetic models suggest that this pattern could be caused by an interaction between recombination rate and the efficacy of natural selection. To test this idea, we examined variation in intron size and recombination rate across the genome of the nematode Caenorhabditis elegans. Interestingly, we found that intron size correlated positively with recombination rate in this species.
Prachumwat, Anuphap; DeVincentis, Laura; and Palopoli, Michael F., "Intron Size Correlates Positively with Recombination Rate in Caenorhabditis elegans" (2004). Biology Faculty Publications. 137.